Michael C Yoon[Author] - Search Results

Year	Number of Results
2021	4
2022	5
2023	1
2024	1

1

Molecular Features of CA-074 pH-Dependent Inhibition of Cathepsin B.

Yoon MC, Christy MP, Phan VV, Gerwick WH, Hook G, O'Donoghue AJ, Hook V. Yoon MC, et al. Biochemistry. 2022 Feb 15;61(4):228-238. doi: 10.1021/acs.biochem.1c00684. Epub 2022 Feb 4. Biochemistry. 2022. PMID: 35119840 Free PMC article.

2

Cathepsin B Dipeptidyl Carboxypeptidase and Endopeptidase Activities Demonstrated across a Broad pH Range.

Yoon MC, Hook V, O'Donoghue AJ. Yoon MC, et al. Biochemistry. 2022 Sep 6;61(17):1904-1914. doi: 10.1021/acs.biochem.2c00358. Epub 2022 Aug 18. Biochemistry. 2022. PMID: 35981509 Free PMC article.

3

Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.

Ashhurst AS, Tang AH, Fajtová P, Yoon MC, Aggarwal A, Bedding MJ, Stoye A, Beretta L, Pwee D, Drelich A, Skinner D, Li L, Meek TD, McKerrow JH, Hook V, Tseng CT, Larance M, Turville S, Gerwick WH, O'Donoghue AJ, Payne RJ. Ashhurst AS, et al. Among authors: yoon mc. J Med Chem. 2022 Feb 24;65(4):2956-2970. doi: 10.1021/acs.jmedchem.1c01494. Epub 2021 Nov 3. J Med Chem. 2022. PMID: 34730959 Free PMC article.

4

A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells.

Mellott DM, Tseng CT, Drelich A, Fajtová P, Chenna BC, Kostomiris DH, Hsu J, Zhu J, Taylor ZW, Kocurek KI, Tat V, Katzfuss A, Li L, Giardini MA, Skinner D, Hirata K, Yoon MC, Beck S, Carlin AF, Clark AE, Beretta L, Maneval D, Hook V, Frueh F, Hurst BL, Wang H, Raushel FM, O'Donoghue AJ, de Siqueira-Neto JL, Meek TD, McKerrow JH. Mellott DM, et al. Among authors: yoon mc. ACS Chem Biol. 2021 Apr 16;16(4):642-650. doi: 10.1021/acschembio.0c00875. Epub 2021 Mar 31. ACS Chem Biol. 2021. PMID: 33787221

5

Discovery of pH-Selective Marine and Plant Natural Product Inhibitors of Cathepsin B Revealed by Screening at Acidic and Neutral pH Conditions.

Phan VV, Mosier C, Yoon MC, Glukhov E, Caffrey CR, O'Donoghue AJ, Gerwick WH, Hook V. Phan VV, et al. Among authors: yoon mc. ACS Omega. 2022 Jul 12;7(29):25346-25352. doi: 10.1021/acsomega.2c02287. eCollection 2022 Jul 26. ACS Omega. 2022. PMID: 35910167 Free PMC article.

6

Distinct Dibasic Cleavage Specificities of Neuropeptide-Producing Cathepsin L and Cathepsin V Cysteine Proteases Compared to PC1/3 and PC2 Serine Proteases.

Yoon MC, Ames J, Mosier C, Jiang Z, Podvin S, O'Donoghue AJ, Hook V. Yoon MC, et al. ACS Chem Neurosci. 2022 Jan 19;13(2):245-256. doi: 10.1021/acschemneuro.1c00653. Epub 2022 Jan 5. ACS Chem Neurosci. 2022. PMID: 34986304 Free PMC article.

7

Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions.

Yoon MC, Solania A, Jiang Z, Christy MP, Podvin S, Mosier C, Lietz CB, Ito G, Gerwick WH, Wolan DW, Hook G, O'Donoghue AJ, Hook V. Yoon MC, et al. ACS Chem Biol. 2021 Sep 17;16(9):1628-1643. doi: 10.1021/acschembio.1c00138. Epub 2021 Aug 20. ACS Chem Biol. 2021. PMID: 34416110 Free PMC article.

8

Distinct Cleavage Properties of Cathepsin B Compared to Cysteine Cathepsins Enable the Design and Validation of a Specific Substrate for Cathepsin B over a Broad pH Range.

Yoon MC, Phan V, Podvin S, Mosier C, O'Donoghue AJ, Hook V. Yoon MC, et al. Biochemistry. 2023 Aug 1;62(15):2289-2300. doi: 10.1021/acs.biochem.3c00139. Epub 2023 Jul 17. Biochemistry. 2023. PMID: 37459182 Free PMC article.

9

Differential Neuropeptidomes of Dense Core Secretory Vesicles (DCSV) Produced at Intravesicular and Extracellular pH Conditions by Proteolytic Processing.

Jiang Z, Lietz CB, Podvin S, Yoon MC, Toneff T, Hook V, O'Donoghue AJ. Jiang Z, et al. Among authors: yoon mc. ACS Chem Neurosci. 2021 Jul 7;12(13):2385-2398. doi: 10.1021/acschemneuro.1c00133. Epub 2021 Jun 21. ACS Chem Neurosci. 2021. PMID: 34153188 Free PMC article.

10

Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK.

Almaliti J, Alhindy M, Yoon MC, Hook V, Molinski TF, O'Donoghue AJ, Gerwick WH. Almaliti J, et al. Among authors: yoon mc. ACS Omega. 2024 Jan 5;9(3):3997-4003. doi: 10.1021/acsomega.3c08629. eCollection 2024 Jan 23. ACS Omega. 2024. PMID: 38284081 Free PMC article.

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